Home » Sangamo BioSciences Reports Data on Program to Treat HIV
Sangamo BioSciences Reports Data on Program to Treat HIV
Sangamo BioSciences has released data from its program to develop a treatment for HIV infection.
The data show that Sangamo's zinc finger DNA binding protein technology has been successfully used in human primary T-cells to disrupt the gene sequence of CCR5, an essential HIV co-receptor.
Sangamo and its clinical collaborator intend to use engineered zinc finger nucleases, or ZFNs, to disrupt the CCR5 gene in T-cells to make them resistant to HIV infection to provide HIV-infected individuals with a reservoir of healthy and uninfectable T-cells. Scientists at Sangamo have engineered ZFNs that can be used to make targeted breaks in DNA for therapeutic gene correction or disruption.
KEYWORDS Drug Pipeline Alert
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