Home » ISIS REPORTS DATA FROM PHASE I LIPID STUDY
ISIS REPORTS DATA FROM PHASE I LIPID STUDY
ISIS REPORTS DATA FROM PHASE I LIPID STUDY
Isis Pharmaceuticals has announced data from a Phase I study in which ISIS 301012 produced rapid reductions of its target, apoB-100, with concomitant reductions in low density lipoprotein (LDL or "bad" cholesterol).
Less than one month following dosing, healthy volunteers achieved a median reduction of 60 percent in apoB-100 and a median reduction of 54 percent in LDL. In the study, six healthy volunteers with mildly elevated cholesterol levels were treated with approximately 350 mg/week of ISIS 301012 for one month. No treatment-related serious adverse events were reported.
KEYWORDS Drug Pipeline Alert
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