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Pharma Blog Watch
Sirtris'
Experimental Obesity Drug (Pharma's Cutting Edge)
In his blog, Fred Cohen writes about results of a preclinical study of Sirtris
Pharmaceuticals' resveratrol recently published in Nature. "In a
nutshell, resveratrol appeared able to prevent many of the deleterious effects
of over-eating/obesity and extended the lives of obese mice."
"First of all, I don't think any line of research today interests me more. For as long as I've been in the biz, I've thought that the holy grail of obesity research is a therapeutic that ameliorates the effects of fat accumulation on cardiovascular risk," he writes. "But besides that I wanted to echo some of the cautious remarks being made in response to it. It's not that I think the research is invalid; it's that I think it's too early to risk taking high doses of resveratrol until more is known about it from human studies, which are recently under way in cancer patients and diabetics."
KEYWORDS Drug Pipeline Alert
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