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Halozyme Therapeutics, a development stage biopharmaceutical company developing
and commercializing recombinant human enzymes, has filed a new drug application
for Enhanze SC, the first product in Halozyme's Enhanze Technology portfolio.
Adherex Technologies and Scynexis have signed an agreement under which Scynexis
will provide comprehensive medicinal and analytical chemistry services to Adherex
with the goal of accelerating and expanding Adherex's small molecule cadherin
antagonist development programs.
Cellegy Pharmaceuticals has reported interim results of a two-center study of
Rectogesic, nitroglycerin (glyceryl trinitrate) ointment 0.2 percent, for the
treatment of symptomatic chronic hemorrhoids.
SCOLR Pharma has achieved positive initial clinical results from the testing
of its OTC 12-hour CDT pseudoephedrine tablets utilizing the company's patented
controlled-delivery technology (CDT).
Following on positive preclinical study results, Dyax is advancing DX-88 for
hereditary angioedema (HAE) into a clinical trial in normal volunteers to evaluate
the safety and pharmacokinetics (PK) of a subcutaneous route of administration.
ICOS has announced that a Phase II study of IC485, an inhibitor of phosphodiesterase
4 (PDE4), in chronic obstructive pulmonary disease did not meet the primary
endpoint of improving lung function.
Connetics has commenced the Phase III clinical program for Primolux (formerly
referred to as OLUX-EF), a super high-potency topical steroid, formulated with
0.05 percent clobetasol propionate in the company's proprietary VersaFoam-EF
emulsion foam delivery vehicle.
Guilford Pharmaceuticals has announced that a Phase III study of Aquavan injection
in patients undergoing elective colonoscopy procedures met its primary efficacy
endpoint without any serious adverse events.
Northwest Biotherapeutics has been issued a patent for antibodies to a protein
that plays an important role in human cancer, both in primary tumors and in
metastasis.