www.fdanews.com/articles/197906-eusa-pharma-to-begin-phase-3-trial-of-siltuximab-for-covid-19-in-us
![COVID-19 Clinical Trial](https://www.fdanews.com/ext/resources/test/Drug-Images4/COVID-19-CLINICAL-TRIAL.gif?t=1585696642&width=430)
EUSA Pharma to Begin Phase 3 Trial of Siltuximab for COVID-19 in U.S.
July 6, 2020
EUSA Pharma is launching a phase 3 clinical trial of its interleukin (IL)-6 antibody siltuximab for the treatment of hospitalized COVID-19 patients with acute respiratory distress syndrome.
The trial will enroll 400 participants, who will either receive the drug or a placebo in addition to standard of care. The study will look for improvements in the patients’ lung function, the length of hospital stays and all-cause mortality.
Marketed as Sylvant, siltixumab is approved for the treatment of multicentric Castleman disease, a rare disease of the lymph nodes and related tissues.