www.fdanews.com/articles/63069-plexxikon-and-roche-enter-partnership-to-develop-targeted-cancer-therapeutic-medicine-plx4032
PLEXXIKON AND ROCHE ENTER PARTNERSHIP TO DEVELOP TARGETED CANCER THERAPEUTIC MEDICINE PLX4032
October 5, 2006
Plexxikon
Inc. and Roche announced they have entered into an agreement to develop and commercialize
PLX4032, Plexxikon's investigational targeted cancer therapy which selectively
inhibits B-RafV600E, a mutated form of the BRAF kinase gene. The BRAFV600E gene
has been associated with increased tumor aggressiveness and decreased survival
in many types of cancers and is a common cancer-causing kinase gene.
Pipeline
Review