BMP-7 PROMOTES REGENERATION OF INJURED KIDNEYS IN PRECLINICAL MODEL OF RENAL DISEASE

Curis has announced that a recent online issue of the Journal of Biological Chemistry contains a report demonstrating that treatment with BMP-7, a signaling protein that was discovered by scientists from Curis, results in repair of kidney injury in a preclinical model of acute kidney disease.

There are currently no adequate therapies to promote repair of injured or diseased kidneys, according to the company. BMP-7 is a regulatory compound that controls a signaling pathway used by the body to maintain the normal health of the kidney and other tissues.

Previous BMP-7 studies have demonstrated its potential therapeutic utility in several different preclinical models of acute and chronic kidney disease, including a possible hormone replacement therapy to treat kidney-associated disorders such as metabolic bone disease and vascular calcification disease.