Large Scale Biology Receives Financing From Chief Executive Officer

Large Scale Biology Corporation received $3,000,000 in term loan financing in exchange for a secured promissory note and accompanying warrant. The loan proceeds will be used for working capital. On April 15, 2005, Large Scale Biology Corporation issued a Promissory Note to Kevin J. Ryan, LSBC's president and chief executive officer and a member of the board of directors. The adjustable rate Note bears interest at Prime Rate plus 200 basis points (currently 7 ¾ percent). The principal of the Note is due on April 17, 2006, with interest paid on a monthly basis, but principal and interest may be prepaid by the company at any time without penalty.

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