APHIOS CORPORATION ANNOUNCES COLLABORATION WITH JAPANESE COMPANIES

Aphios Corporation today announced that it has entered a Research and Development collaboration with two Japanese companies, Bio Research Corporation of Yokohama, Yokohama, Japan and Tokyo Supply, Ltd., Minato, Japan to develop an orally-bioavailble anti-cancer therapaeutic. The collaborators plan to develop a water-soluble paclitaxel prodrug. The molecule is a combination of a paclitaxel molecule, the potent anticancer drug, and a sugar molecule that enhances solubility. This molecular combination is not bioactive prior to treatment and is significantly more water-soluble than paclitaxel. The water-soluble nature of this novel therapeutic allows for oral digestion rather than intra-venous (IV) injection.

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