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Regeneron’s antibody cocktail, REGEN-COV, has demonstrated a reduced risk of death for COVID-19 patients in one arm of the UK’s Recovery trial that is investigating multiple potential COVID-19 treatments. Read More
AstraZeneca’s monoclonal antibody cocktail, AZD7442, failed to prevent symptomatic COVID-19 infection in a late-stage study of individuals recently exposed to the SARS-CoV-2 virus. Read More
The data provide “the first comparative evidence” that the Imbruvica combination has the potential to extend time to disease progression vs. standard therapy,” the trial’s lead investigator said. Read More
Novavax said it plans to file for FDA Emergency Use Authorization (EUA) of its two-dose COVID-19 vaccine in the third quarter, supported by the strong efficacy data from its late-stage trial in which the recombinant DNA-based vaccine proved 100 percent effective in preventing moderate and severe disease, and more than 90 percent effective at preventing symptomatic infections. Read More
Trial investigator Ali Taher said the findings demonstrate that Reblozyl sustained elevated hemoglobin levels in most patients “regardless of their baseline hemoglobin status.” Read More
Bristol Myers Squibb (BMS) is evaluating its CAR-T therapy Breyanzi for use during earlier lines of therapy for adult lymphoma patients and said early treatment significantly improved patient outcomes in a late-stage trial. Read More