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Vertex Pharmaceuticals has decided to give up on its experimental VX-814, a small molecule drug for the rare genetic disease Alpha-1 antitrypsin deficiency (AATD), canning the drug’s development after seeing lackluster results from an early phase 2 trial. Read More
More than a month has passed since AstraZeneca’s phase 3 COVID-19 vaccine trial was paused due to a potential adverse event, but few solid details have emerged from ongoing safety reviews by the FDA and the UK drugmaker. Read More
Pfizer said it will add participants as young as 12 to the global phase 3 trial of its COVID-19 vaccine candidate to glean more information on how the treatment affects different age groups. Read More
The first participant has been dosed in Vaxart’s phase 1 study of an oral COVID-19 vaccine tablet the company is developing as an alternative to injectable vaccines. If approved, it would be the first-ever vaccine in tablet form. Read More
A clinical trial of Eli Lilly’s antibody candidate treatment for COVID-19 was paused Tuesday following a safety incident — awkward timing as the company has just applied to the FDA for an Emergency Use Authorization (EUA) for the product. Read More
Eli Lilly says its rheumatoid arthritis (RA) therapy Olumiant (baricitinib) combined with Gilead Sciences’ antiviral remdesivir reduced COVID-19 patient recovery time by 12.5 percent, or from eight to seven days, over remdesivir alone. Read More
A late-stage trial of Russia’s Sputnik V COVID-19 neutralizing antibody vaccine is now underway in the United Arab Emirates, the Kremlin said. Read More